Cluster Headache 2

Cluster Headache TriggersUnlike migraine and tension-type headache, cluster headache is generally not associated with triggers such as diet, hormonal changes or stress. But in some people with cluster headache is a heavy drinker and a heavy smoker. After a cluster period begins, the consumption of alcohol can lead to very severe headache within a few minutes. For this reason a lot of people with cluster headache abstain from alcohol during the cluster. Triggers are the use of drugs such as nitroglycerin, which is used in patients with heart disease.Starters often cluster period after disruption of normal sleep patterns, such as during holidays or when starting a new job or a new working hours. Some people with cluster headache also had apnea during sleep, a condition where a wall collapse while the throat and obstruct the airway during sleep repeatedly.Increased Sensitivity of Line NervesSevere pain in cluster headache centered behind or around the eyes, in an area supplied by the trigeminal nerve, a major pain pathway. Stimulation of this nerve produces an abnormal reaction of the arteries that supply blood to the head. The blood vessels will dilate and cause pain.Some of the symptoms of cluster headache as watery eyes, runny nose or congestion, and, as well as a difficult eyelids raised involving the autonomic nervous system. The nerves that are part of this system form a line at the base of the brain. When the trigeminal nerve in the activation, causing pain in the eyes, the autonomic nervous system is also activated by the so-called trigeminal autonomic reflex. The researchers believe that there is still an unknown process that involves inflammation or abnormal blood vessel activity in this region that may be involved causing headaches.Abnormal function of the hypothalamusAttacks usually occur with cluster-like setting the clock 24 hours a day. Cycle cluster periods often follow the pattern of the season in a year. This pattern suggests that the body's biological clock involved. In the human biological clock located in the hypothalamus, which is located deep in the brain. Of the many functions of the hypothalamus, this section controls the sleep wake cycle and other internal rhythms. Hypothalamic abnormalities might explain the timing and cycles in cluster headache. Studies have found increased activity in the hypothalamus during the cluster headache. Increased activity is not found in people with other headaches such as migraine.The study also found that people who have abnormal levels of certain hormones, including melatonin and testosterone, the hormone levels increase from the cluster. Changes in hormones are believed to be due to a problem with the hypothalamus. Other researchers have found that people with cluster headache have a larger hypothalamus than those who do not have a cluster headache. It is still not known why these disorders can happen like that.
5. PathophysiologyPathophysiology of cluster headache is not fully understood. Periodicity associated with the influence of hormones on the hypothalamus (especially the nucleus suprachiasmatik). Recently, functional neuroimaging with positron Emisión tomography (PET) and anatomical imaging with voxel-base morphometry have identified the posterior part of the substantia grisea of ​​the hypothalamus as a key area of ​​damage on the basis of cluster headache.Pain in cluster headache thought to be produced at the complex perikarotid / cavernosal sinus. This area receives sympathetic and parasympathetic impulses from the brain stem, may mediate the autonomic phenomena during the attack. Exact role of immunological factors and vasoregulator, as well as the influence of hypoxemia and hypocapnia in cluster headache remains controversial.

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