Hormonal Contraceptives part I


CHAPTER I
INTRODUCTION

Contraception is an attempt to prevent kehamilan.upaya it may be temporary, may also be permanent contraceptive use is one of the variables that affect fertilitas. Hormonal contraception is one of the most effective methods of contraception and reversible to prevent conception. Hormonal contraception, hormonal contraception) Most types of hormones contained in hormonal contraceptives are synthetic hormones types, except those contained in the depot medroxyprogesterone acetate (MPA depot), which type of hormone is a type of natural progesterone.

Most of the hormonal contraceptive is administered orally. Today the available various types of hormonal contraception that can be confusing to physicians and the public. The important thing is to know the type of hormone, dose, mode of operation, side effects, and ways of administration. Before advocating a woman using hormonal contraceptives, it is necessary gynecologic history and a careful examination. To all women need to be explained about how to use, security and the possible risks and side effects that may occur.

CHAPTER II
HORMONAL CONTRACEPTIVES

II.1. History
The influence of the corpus luteum which has been known to inhibit ovulation in the early 20th century. In 1921 Haberlandt ovarian transplants who are pregnant laboratory animals to other animals of the same species. He found temporary infertility in animals that received transplants. In 1930 Allen perform isolation of progesterone, and in subsequent years Bickenbach and Von Massenbach found that progesterone, testosterone, and estrogen can inhibit ovulation. However, until the year 1950 this steroid hormone has not yet found a drug antifertilitas, but many were investigated to produce kortison.

It was only in the 1950's after Pincus, Chang and Rock found that administration of progesterone per os on days 5 to 25 menstrual cycle can inhibit ovulation, steroid hormones are used for purposes of contraception. The first experiments with the use of oral contraceptives and mestranol noretinodrel in Puerto Rico in 1956 proved a very high efficiency as kontrasepsi.
 
Since then the development of hormonal contraception continues. In 1960, a combination estrogen-progesterone pill into use. Skuensial pill was introduced in 1963. Since 1965 until now widely held dose adjustment or the use of progesterone alone, hence the mini pill, and others. These developments are generally intended to seek a hormonal contraceptive that has a high efficiency, minimal side effects, and patient complaints are the smallest.

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